Welcome to the Neurotrauma and Repair Laboratory where we are studying 1) the biomechanics of traumatic brain injury and 2) why brain cells die after a traumatic brain injury. With the knowledge that we gain, we hope to develop better protection strategies to prevent head injuries, to develop new therapies for treating head injuries, and to develop strategies to help repair the damage that does occur. Please, use these pages to learn more about what we do.

NTAR Laboratory

Recent News and Events

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2017

January 26, 2017, Edward Vogel III successfully defends his thesis titled "Pathobiological Mechanisms and Treatment of Electrophysiological Dysfunction Following Primary Blast-Induced Traumatic Brain Injury". Congratulations Eddie!

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2016

September 2016, The Neurotrauma and Repair Laboratory welcomes a new graduate student: Nevin Varghese (B.S.E. Rutgers University).

July 13, 2016, Professor Barclay Morrison gives an invited talk titled "Biomechanics for Prevention: Preventing synergy of repetitive mTBI" for the Big Ten–Ivy League Traumatic Brain Injury Research Collaboration, Philadelphia, PA.

June 16, 2006, Professor Barclay Morrison gives an invited talk titled "Studying repetitive TBI in a culture dish" for the Center for Injury Epidemiology and Prevention, Columbia University, NY.

May 6, 2016, Professor Barclay Morrison gives an invited talk titled "Comparing primary and tertiary phases of blast traumatic brain injury with an in vitro model" for the Department of Anatomy & Neurobiology, Virginia Commonwealth University, VA.

April 22, 2016, Gwen Effgen successfully defends her thesis titled "Improving Outcomes after Repetitive Mild Traumatic Brain Injury from Shockwave Exposure or Stretch Injury".  Congratulations Gwen!

February 2016, Sowmya Sundaresh and Sonali Ahuja pass their qualifying examinations, officially becoming Ph.D. students!  Congratulations Sowmya and Sonali!

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2015

September 17, 2015, Professor Barclay Morrison gives an invited talk titled ‘Heading off Damage: New Insights in Traumatic Brain Injury’ for Columbia University’s Mortimer B. Zuckerman Mind Brain Behavior Institute, Stavros Niarchos Foundation Brain Insight Lecture Series, Columbia University, NY

September 10, 2015, Professor Barclay Morrison chairs two sessions titled 'Brain/Head Injury/Tissue Biomechanics' and 'Blast Injury' at the International Research Council on Biomechanics of Injury, Lyon, France.

June 23, 2015, Professor Morrison gives an invited talk titled 'Traumatic brain injury' for the GEM4 2015 Summer Institute, Carnegie Mellon University, PA

June 2015, The Neurotrauma and Repair Laboratory welcomes visiting PhD student, Elena Chierto, from Universite Paris Descartes.

May 15, 2015, Christopher Hue successfully defends his thesis titled "Blood-Brain Barrier Dysfunction and Repair after Blast-Induced Traumatic Brain Injury". Congratulations Chris!

April 8, 2015, Professor Barclay Morrison chairs a session titled 'Stretchable Electronic Materials for Transducers, Biosensors and Optical Devices I' at the Material Research Society

February 6, 2015, Professor Morrison gives an invited talk titled 'Learning deficits in hippocampal slice cultures after traumatic brain injury' for the Biomedical Engineering Seminar Series, New Jersey Institute of Technology, NJ

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2014

December 4, 2014, Professor Morrison gives an invited talk titled 'Neuronal network function is altered after in vitro traumatic brain injury' for the Neuroscience Seminar, Tulane University, LA

November 12, 2014, Professor Morrison gives an invited talk titled 'Mild traumatic brain injury - in a dish!?' for First Year Seminars in Modern Biology, Columbia University, NY

October 14, 2014, Professor Morrison gives an invited talk titled 'Traumatic brain injury alters electrophysiological function in organotypic brain slice cultures' for The Head Injury Center CNS Injury Seminar Series, University of Pennsylvania, PA

September 23, 2014, Professor Morrison gives an invited talk titled 'Biomechanics at the mesoscopic scale: Knowledge and tools to define tolerance' for Army Research Laboratory, Aberdeen Proving Grounds, MD

September 11, 2014, Professor Barclay Morrison chairs a session titled 'Tissue Biomechanics - Tissue Characterization I & II' at the International Research Council, Berlin, Germany.

September 4, 2014, Michael Lamprecht successfully defends his thesis titled "A Potential Combination Therapy for Traumatic Brain Injury: 17β-Estradiol and Memantine". Congratulations Mike!

September 2014, The Neurotrauma and Repair Laboratory welcomes two new graduate students Sonali Ahuja (B.S.E. Rutgers University) and Sowmya  (B.S.E. Stony Brook University).

May 2014, Andrew (Woo Hyeun) Kang successfully defends his thesis titled "Reducing the Societal Costs of Traumatic Brain Injury: Astrocyte-Based Therapeutics and Functional Injury Tolerance of the Living Brain". Congratulations Andrew!

March 3, 2014, Professor Morrison gives an invited talk titled 'Traumatic brain injury: at the intersection of neuroscience and biomechanics' for the Current Issues in Neuroscience seminar series, Teacher College, Columbia University, NY

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2013

December 10, 2013, Professor Morrison gives an invited talk titled 'From biomechanics to cerebral edema after traumatic brain injury' for Visiting Professor Research Seminar, Department of Anesthesiology, Columbia University

October 2, 2013, Professor Morrison gives an invited talk titled ‘Brain trauma from Blast’ for First Year Seminars in Modern Biology, Columbia University, NY

September 28, 2013, Professor Barclay Morrison chairs a session titled ‘Clinical Biomechanics’ at the annual Biomedical Engineering Society conference, Seattle, WA

September 13, 2013, Professor Barclay Morrison chairs a session titled ‘Tissue Characterization III’ at the International Research Council on Biomechanics of Injury Conference, Gothenburg, Sweden

September 12, 2013, Professor Barclay Morrison chairs a session titled ‘Tissue Characterization II’ at the International Research Council on Biomechanics of Injury Conference, Gothenburg, Sweden

August 10, 2013 Professor Morrison gives an invited talk titled “Better Strategies to Prevent Brain Injuries”, for Aspen BrainLab, Aspen, CO

May 31, 2013, The Neurotrauma and Repair Laboratory welcomes the 5th grade science class from the Collegiate School to learn about traumatic brain injury and why wearing a helmet is important!

April 2013, Professors Barclay Morrison and King Yang of Wayne State University have been asked to co-organize a multi-day minisymposium on Traumatic Brain Injury Biomechanics for the 17th U. S. National Congress on Theoretical and Applied Mechanics to be held at Michigan State University from June 15-20, 2014

March 21, 2013 Professor Morrison gives an invited talk titled ‘Traumatic Brain Injury: Inertia- and Blast-Injuries and an Edema Therapy’ for Grand Rounds, Department of Neurosurgery, Columbia University Medical Center, NY

Graduate student Edward Vogel receives his Masters of Science and Masters of Philosophy degree. Congratulations Eddie!

March 15, 2013, Graduate student Edward Vogel passes his qualifying examination, officially becoming a Ph.D. student! Congratulations Eddie!

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2012

November 14, 2012 Professor Morrison gives an invited talk titled ‘Brain trauma: Biomechanical Insights’ for First Year Seminars in Modern Biology, Columbia University, NY

November 2012, Congratulations to Mr. Syed Haider for receiving an Oral Presentation Award in Engineering, Mathematics and Physics from the Annual Biomedical Research Conference for Minority Students for his study titled ‘Increased solute permeability of an in vitro blood-brain barrier model exposed to blast overpressure’

October 27, 2012, Professor Barclay Morrison chairs a session titled ‘Neuro Trauma Injury & Repair II’ at the annual Biomedical Engineering Society conference, Atlanta, GA

October 26, 2012, Professor Barclay Morrison chairs a session titled ‘Neuro Trauma Injury & Repair I’ at the annual Biomedical Engineering Society conference, Atlanta, GA

October 16, 2012, The Neurotrauma and Repair Laboratory is featured in an article titled ‘Understanding the biomechanics of brain injury to find treatments for injured soldiers, athletes', featured in the Columbia University Record

September 2012, Professor Barclay Morrison is appointed a Council Member of the International Research Council on Biomechanics of Injury

September 2012, Congratulations to Mr. Chris Hue for receiving the Murray Mackay Young Researcher Award from the International Research Council on Biomechanics of Injury for his study titled ‘Blast-induced disruption of an in vitro blood-brain barrier model’

July 2012, Professor Barclay Morrison is appointed Associate Editor of the Journal of Biomechanical Engineering

July 2012, Congratulations to Dr. John Finan for receiving a Charles H. Revson Senior Fellowship in the Biomedical Sciences for ‘Anti-edema treatments for brain swelling’

May 30, 2012, The Neurotrauma and Repair Laboratory welcomes the 5th grade science class from the Collegiate School to learn about traumatic brain injury and why wearing a helmet is important!

May 2012, Congratulations to Mr. Chris Hue for receiving a National Science Foundation Graduate Research Fellowship for ‘Engineering Novel Cell Penetrating Peptides for Therapeutic Delivery Across the Blood-Brain Barrier to Specific Cellular Targets’

May 2012, Congratulations to Mr. Eddie Vogel for receiving a National Defense Science and Engineering Graduate Research Fellowship for ‘Quantitative Thresholds For Blast Traumatic Brain Injury’

March 3, 2012, The Neurotrauma and Repair Laboratory participates in the Science Expo at the School at Columbia University, inspiring our excitement for science and engineering in young people

January 23, 2012 Professor Barclay Morrison organizes and chairs a session titled ‘Blast traumatic brain injury’ at the 45th Winter Conference on Brain Research, Snowbird, UT

January 12, 2012 Professor Morrison gives an invited talk titled ‘Biomechanical insight to traumatic brain injury from brain slice models’ for the Center for Neuroscience & Regenerative Medicine, Uniformed Services University of the Health Sciences, MD.

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2011

November 29-30, 2011 Professor Barclay Morrison Sigfried Bauer (Johannes-Kepler Universitat Linz), Kunigunde Cherenack (ETH), and Tsuyoshi Sekitani (University of Tokyo) organize a 2-day symposium on Compliant electronics and photonics at the Fall Material Research Society Meeting

November 9, 2011, Professor Barclay Morrison gives and invited talk to the Safar Center for Resuscitation Research, University of Pittsburgh Medical Center titled” Traumatic Brain Injury Tolerances: In Vitro Insights”.

November 7-8th, 2011, Professor Barclay Morrison serves as Conference Chair for the 6th International Conference on Biomechanics sponsored by the International Association of Science and Technology for Development (IASTED). 

October 12-14, 2011, Professors Barclay Morrison and Lance Kam (Columbia University) serve as Track Chairs of the Neural Engineering Track for the annual Biomedical Engineering Society meeting in Hartford, CT.

October 2011, Professor Barclay Morrison accepts a position as a Review Editor for Frontiers in Neurotrauma.

September 2011, The Neurotrauma and Repair Laboratory welcomes its newest graduate student Eddie W. Vogel (B.S.E. University of Maryland).

June 2011, Neurotrauma and Repair Laboratory graduate student Mr. Mike Lamprecht is a finalist in the student competition at the Annual National Neurotrauma Symposium for his work titled “Combinational Drug Therapies as Treatment for Traumatic Brain Injury.”

June 2011, Neurotrauma and Repair Laboratory graduate student Mr. Chris Hue receives a travel award from the Annual National Neurotrauma Symposium for his work titled “Blast overpressure induces disruption of brain endothelial monolayer integrity.”

June 2011, Neurotrauma and Repair Laboratory graduate student Mr. Mike Lamprecht receives a travel award from the Annual National Neurotrauma Symposium for his work titled “Combinational Drug Therapies as Treatment for Traumatic Brain Injury.”

May 26, 2011, The Neurotrauma and Repair Laboratory welcomes the 5th grade science class from the Collegiate School to learn about traumatic brain injury and why wearing a helmet is important!

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2010

September 2010, Professor Barclay Morrison (Co-PI), Professor David F. Meaney (University of Pennsylvania), and Professor C.R. “Dale” Bass (Duke University) are awarded a Multi-University Research Initiative (MURI) from the Army Research Laboratory, DoD titled “Blast Induced Thresholds for Neural Networks (BITNeT)” to study tolerance criteria to blast for traumatic brain injury.

September 2010, Congratulations to Dr. Melissa J. Simon on successfully defending her Ph.D. thesis titled “Delivery to Brain Cells using Cell-Penetrating Peptides: Evaluation of the TAT Peptide and Development of Techniques for Identifying Novel Peptides”.

Septemeber 2010, The Neurotrauma and Repair Laboratory welcomes two new graduate students Gwen B. Effgen (B.A. Barnard College) and Chris D. Hue (B.S.E. CCNY).

August 12, 2010, Professor Barclay Morrison gives and invited lecture titled “Heterogeneous material properties and tolerance criteria for brain injury models” for the DoD Brain Injury Computational Modeling Expert Panel, FL.

On August 3, 2010, Professor Barclay Morrison will be giving an invited presentation titled “Determining a mechanical tolerance criterion for neuron function within the hippocampus” for the 6th World Congress on Biomechanics in Singapore.  He will also be chairing a session focused on “Head/Brain Injury - Tolerances”.

July 2010, The Neurotrauma and Repair Laboratory welcomes its newest postdoctoral fellow, Dr. John D. Finan who received his Ph.D. from Duke University in Professor Farshid Guilak’s laboratory.

Ben Elkin is a finalist in the Ph.D. Student Poster Competition at the ASME Summer Bioengineering Conference from June 16-19, 2010 for his study titled “Mechanical properties of the rat brain: effect of age and anatomical region”.  Congratulations Ben!

Professor Barclay Morrison gives an invited presentation for the National Neurotrauma Symposium on June 15, 2010 titled “Outcome measures in in vitro modeling of TBI / validation of in vitro models”.

Ben Elkin receives a Student Travel Grant to attend the 28th National Neurotrauma Symposium from June 14-17, 2010 to present his work titled “The effect of chondroitinase ABC on brain tissue swelling in vitro”.  Congratulations Ben!

June 2010, Professor Barclay Morrison and Professor David I. Shreiber (PI) of Rutgers University are awarded a grant from the New Jersey Commission of Brain Injury Research titled “Evaluation of genipin as a multi-potent therapeutic agent following brain injury”.

Professor Barclay Morrison chairs a discussion panel on “Brain Injuries and Neuro-Regeneration” as part of the Biomedical Science and Engineering Conference, Oak Ridge National Laboratory, May 26, 2010.

Professor Barclay Morrison participates in the IEEE EMBS Forum on Grand Challenges in Neuroengineering held May 7-8, 2010

On May 5, 2010, Professor Barclay Morrison gave an invited presentation titled “Material properties and failure criteria for brain: understanding brain injury biomechanics” for the Department of Chemistry, Chemical Biology, and Biomedical Engineering at the Stevens Institute of Technology.

Ben Elkin successfully defends his Ph.D. thesis on April 21, 2010 and was awarded the degree with distinction for its outstanding quality.  The award of distinction is reserved for theses judged to be in the top 10% across the entire University.  Congratulations Ben!

Professor Barclay Morrison and his co-organizers, Stephanie Lacour (Cambridge University) John Rogers (University of Illinois, Urbana-Champagne), Siegfried Bauer (Johannes-Kepler Universität Linz) organized a 2-day symposium entitle “Stretchable Electronics and Conformal Biointerfaces” as part of the Spring Material Research Society meeting, April 8-9, 2010.

On March 28, 2010, Professor Barclay Morrison gave an invited presentation titled “Mechanical properties of anatomical structures of the rat brain” for the Northeast Bioengineering Conference.  Professor Morrison also chaired a session title “Imaging of Biomaterials”.

Ben Elkin wins a student award at the 36th Northeast Bioengineering Conference from March 26-28, 2010 for his presentation titled “Chondroitin Sulfate Proteoglycans Contribute to Brain Tissue Swelling”. Congratulations Ben!

On March 18, 2010, Professor Barclay Morrison gave an invited presentation titled “Brain material properties and tolerance criteria: critical ingredients for computational models of brain injury” for the Mechanical Engineering department at the City College of New York.

On February 11, 2010, Professor Barclay Morrison gave a seminar in the Electrical Engineering Department at Princeton University entitled “Compliant tissue-electronics interfaces for biomedical studies”.

February 2010, Professor Barclay Morrison is named an Associated Editor for the journal BMC Neuroscience , an open-access, peer-reviewed journal with an impact factor of 3.09.

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2009

Zhe Yu successfully defends his Ph.D. thesis on December 10th, 2009 becoming Professor Morrison’s first Ph.D. student to graduate.  Congratulations Zhe!

Professor Barclay Morrison presented for Grand Rounds in the Department of Neurosurgery at the Columbia University Medical Center on November 12, 2009.  The title of his presentation was “Studying traumatic brain injury through a combination of biomechanics and cell biology”.

Professor Barclay Morrison will be giving the opening keynote address for the annual International Research Council on Biomechanics of Injury conference on September 9, 2009: “Progress on tissue-level, functional tolerance criteria and material properties of the living brain with anatomical resolution.”

Professor Barclay Morrison will be giving an invited presentation on September 3, 2009 for the “Neural Injury” session at the Engineering in Medicine and Biology Conference.  The title of his talk is “Quantification of functional alterations after in vitro traumatic brain injury.”

Professor Barclay Morrison will be giving an invited presentation on September 4, 2009 for the “Neural Sensing and Applications” session at the Engineering in Medicine and Biology Conference.  The title of his talk is “Neural sensing of electrical activity with stretchable microelectrode arrays.”

Professor Barclay Morrison is the organizer and chair with co-organizer and co-chair Dr. Michelle LaPlaca from Georgia Institute of Technology of a special session titled “Neural Trauma” at the Engineering in Medicine and Biology Conference to be held in Minneapolis, MN from September 2-6, 2009.

Professor Barclay Morrison gave an invited presentation on June 17, 2009 in Barga, Italy as part of the Nanotechnology for the Study of Cellular and Molecular Interactions Conference, organized by Engineering Conferences International. The title of his talk was “Vertically aligned carbon nanofiber arrays for electrophysiological and electrochemical recordings from brain slices”.  In addition, Professor Morrison and Dr. Stephanie Lacour of Cambridge University organized a session title “Nanoscience for Neuroscience”.

On June 5, 2009, Professor Barclay Morrison presented for the Grand Rounds in the Department of Neurosurgery, Medical College of Wisconsin. The title of his talk was “Brain tissue heterogeneity and implications for traumatic brain injury.”

Professor Barclay Morrison, in collaboration with Dr. Scott Banta as principal investigator, is awarded a grant from the National Science Foundation titled “Directed evolution of specific cell penetrating peptides.”

On April 6, 2009, Professor Barclay Morrison gave an invited talk for the Irving Institute Center for Clinical and Translational Research Nanotechnology Seminar Series at the Columbia University Medical Center.  The title of his talk was “Vertically aligned carbon nanofiber arrays for neuroscience,” in which he described collaborative studies with Drs. Nance Ericson and Tim McKnight from Oak Ridge National Laboratory to implement a novel dual sensing microelectrode array to study brain function.

Mike Lamprecht is the recipient of a prestigious National Science Foundation Graduate Research Fellowship.  The Graduate Research Fellowship Program invests in graduate education for a cadre of diverse individuals who demonstrate their potential to successfully complete graduate degree programs in disciplines relevant to the mission of the National Science Foundation.  Congratulations, Mike!

Mike Lamprecht passed the qualifying exam, officially becoming a Ph.D. student.  Congratulations, Mike!

Ph.D. candidate Zhe Yu successfully defends his thesis proposal.  Congratulations, Zhe!

Professor Barclay Morrison gave an invited talk at the annual Biomedical Science and Engineering Conference at Oak Ridge National Laboratory on March 19, 2009.  The tile of his talk was “Modeling traumatic brain injury in vitro: functional changes in the absence of cell death.”

MIT’s Technology Review for his work on stretchable microelectrode arrays in “Stretchy Electrodes Wire Up Cells.”  This work is in collaboration with Dr. Sigurd Wagner at Princeton University and Dr. Stephanie Lacour at Cambridge University.

Professor Barclay Morrison, in collaboration with Dr. Elisa Konofagou as principal investigator, was awarded a grant from the National Institute of Biomedical Imaging and Bioengineering for studies on the “Optimization of ultrasound-facilitated blood-brain barrier opening.”

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