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Ultrasound Elasticity Imaging Laboratory

Columbia University

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      • Elisa Konofagou
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Wei-Ning "Winnie" Lee, M.S. (Former Ph.D. Student)

Academic Qualifications

  • M.S., Electrical Engineering, National Taiwan University (Taipei, Taiwan), 2003
  • B.S., Electrical Engineering, National Taiwan University (Taipei, Taiwan), 2001

Biography

Wei-Ning Lee was born in Taichung, Taiwan, on August 27, 1979. She received the B.S. and M.S. degrees from National Taiwan University, Taipei, Taiwan, R.O.C. in 2001 and 2003, respectively, both in Electrical Engineering. She was a research assistant with the department of Electrical Engineering from 2003 to 2004. In September 2004, she enrolled in Columbia University's PhD program. Her current research interest is cardiac ultrasound.

Publications

To obtain a bibliography of all of Ms. Lee's publications, click here to download the complete list (in BibTeX format).

Journal Articles

  • Reduced thoracolumbar fascia shear strain in human chronic low back pain
  • Hélène M. Langevin, James R. Fox, Cathryn Koptiuch, Gary J. Badger, Ann C. Greenan-Naumann, Nicole A. Bouffard, Elisa E. Konofagou, Wei-Ning Lee, John J. Triano, Sharon M. Henry
  • BMC Musculoskeletal Disorders, Volume 12, Number 203, Pages 1-11, September 2011
  • Digital Object Identifier: 10.1186/1471-2474-12-203
  • Download Full Text (PDF) | Download Citation (BibTeX)
  • Physiologic cardiovascular strain and intrinsic wave imaging
  • Elisa E. Konofagou, Wei-Ning Lee, Jianwen Luo, Jean Provost, Jonathan Vappou
  • Annual Review of Biomedical Engineering, Volume 13, Pages 477-505, August 2011
  • Digital Object Identifier: 10.1146/annurev-bioeng-071910-124721
  • Download Full Text (PDF) | Download Citation (BibTeX)
  • Imaging the electromechanical activity of the heart in vivo
  • Jean Provost, Wei-Ning Lee, Kana Fujikura, Elisa E. Konofagou
  • Proceedings of the National Academy of Sciences of the USA, Volume 108, Number 21, Pages 8565-8570, May 2011
  • Digital Object Identifier: 10.1073/pnas.1011688108
  • Download Full Text (PDF) | Download Citation (BibTeX)
  • In vivo study of myocardial elastography under graded ischemia conditions
  • Wei-Ning Lee, Jean Provost, Kana Fujikura, Jie Wang, Elisa E. Konofagou
  • Physics in Medicine and Biology, Volume 56, Number 4, Pages 1155-1172, February 2011
  • Digital Object Identifier: 10.1088/0031-9155/56/4/017
  • Download Full Text (PDF) | Download Citation (BibTeX)
  • Electromechanical wave imaging of normal and ischemic hearts in vivo
  • Jean Provost, Wei-Ning Lee, Kana Fujikura, Elisa E. Konofagou
  • IEEE Transactions on Medical Imaging, Volume 29, Number 3, Pages 625-635, March 2010
  • Digital Object Identifier: 10.1109/TMI.2009.2030186
  • Download Full Text (PDF) | Download Citation (BibTeX)
  • Fundamental performance assessment of 2-D myocardial elastography in a phased array configuration
  • Jianwen Luo, Wei-Ning Lee, Elisa E. Konofagou
  • IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, Volume 56, Number 10, Pages 2320-2327, October 2009
  • Digital Object Identifier: 10.1109/TUFFC.2009.1313
  • Download Full Text (PDF) | Download Citation (BibTeX)
  • Preliminary validation of angle-independent myocardial elastography using MR tagging in a clinical setting
  • Wei-Ning Lee, Zhen Qian, Christina L. Tosti, Truman R. Brown, Dimitris N. Metaxas, Elisa E. Konofagou
  • Ultrasound in Medicine and Biology, Volume 34, Number 12, Pages 1980-1997, December 2008
  • Digital Object Identifier: 10.1016/j.ultrasmedbio.2008.05.007
  • Download Full Text (PDF) | Download Citation (BibTeX)
  • Angle-independent and multi-dimensional myocardial elastography - from theory to clinical validation
  • Wei-Ning Lee, Elisa E. Konofagou
  • Ultrasonics, Volume 48, Number 6-7, Pages 563-567, November 2008
  • Digital Object Identifier: 10.1016/j.ultras.2008.07.005
  • Download Full Text (PDF) | Download Citation (BibTeX)
  • A composite high-frame-rate system for clinical cardiovascular imaging
  • Shougang Wang, Wei-Ning Lee, Jean Provost, Jianwen Luo, Elisa E. Konofagou
  • IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, Volume 55, Number 10, Pages 2221-2233, October 2008
  • Digital Object Identifier: 10.1109/TUFFC.921
  • Download Full Text (PDF) | Download Citation (BibTeX)
  • Theoretical quality assessment of myocardial elastography with in vivo validation
  • Wei-Ning Lee, Christopher M. Ingrassia, Simon D. Fung-Kee-Fung, Kevin D. Costa, Jeffrey W. Holmes, Elisa E. Konofagou
  • IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, Volume 54, Number 11, Pages 2233-2245, November 2007
  • Digital Object Identifier: 10.1109/TUFFC.2007.528
  • Download Full Text (PDF) | Download Citation (BibTeX)
  • A novel, view-independent method for strain mapping in myocardial elastography: eliminating angle- and centroid-dependence
  • Ioannis K. Zervantonakis, Simon D. Fung-Kee-Fung, Wei-Ning Lee, Elisa E. Konofagou
  • Physics in Medicine and Biology, Volume 52, Number 14, Pages 4063-4080, July 2007
  • Digital Object Identifier: 10.1088/0031-9155/52/14/004
  • Download Full Text (PDF) | Download Citation (BibTeX)

Conference Papers and Presentations

  • Electromechanical wave imaging for noninvasive mapping of the 3D electrical activation sequence in vivo
  • Jean Provost, Wei-Ning Lee, Kana Fujikura, Elisa E. Konofagou
  • American Heart Association Scientific Sessions (Chicago, IL, USA), November 13 to 17, 2010
  • Download Citation (BibTeX)
  • Mapping the electrical activation sequence of the heart using electromechanical wave imaging: a validation study in canines
  • Jean Provost, Wei-Ning Lee, Kana Fujikura, Elisa E. Konofagou
  • 9th International Tissue Elasticity Conference (Snowbird, UT, USA), October 16 to 19, 2010
  • Download Citation (BibTeX)
  • A noninvasive direct method for cardiac mapping: electromechanical wave imaging
  • Jean Provost, Stanley J. Okrasinski, Wei-Ning Lee, Kana Fujikura, Elisa E. Konofagou
  • 31st Heart Rhythm Society Annual Scientific Sessions (Denver, CO, USA), May 12 to 15, 2010
  • Download Citation (BibTeX)
  • Frame rate dependence of myocardial elastography estimates using a physiologic 3D biventricular finite-element model of the heart with preliminary in vivo validation
  • Wei-Ning Lee, K. M. Parker, Jianwen Luo, Jeffrey W. Holmes, Elisa E. Konofagou
  • IEEE International Ultrasonics Symposium (Rome, Italy), September 18 to 21, 2009
  • Download Citation (BibTeX)
  • Electromechanical wave imaging: non-invasive localization and quantification of partial ischemic regions in vivo
  • Jean Provost, Wei-Ning Lee, Kana Fujikura, Elisa E. Konofagou
  • IEEE International Ultrasonics Symposium (Rome, Italy), September 18 to 21, 2009
  • Download Citation (BibTeX)
  • In vivo validation of myocardial elastography to quantify variable levels of myocardial ischemia
  • Wei-Ning Lee, Jean Provost, Kana Fujikura, Jie Wang, Elisa E. Konofagou
  • 34th International Symposium on Ultrasonic Imaging and Tissue Characterization (Arlington, VA, USA), June 10 to 12, 2009
  • Invited Contribution
  • Download Citation (BibTeX)
  • Noninvasive imaging of pulse wave propagation and assessment of wall properties in human abdominal aortas in vivo
  • Jianwen Luo, Wei-Ning Lee, Shougang Wang, Elisa E. Konofagou
  • American Institute of Ultrasound in Medicine Annual Convention (New York, NY, USA), April 2 to 5, 2009
  • Download Citation (BibTeX)
  • In vivo validation of left-ventricular strains at variable levels of myocardial ischemia
  • Wei-Ning Lee, Jean Provost, Kana Fujikura, Jie Wang, Elisa E. Konofagou
  • American Institute of Ultrasound in Medicine Annual Convention (New York, NY, USA), April 2 to 5, 2009
  • Download Citation (BibTeX)
  • Pulse wave imaging of human abdominal aortas in vivo
  • Jianwen Luo, Wei-Ning Lee, Shougang Wang, Elisa E. Konofagou
  • Proceedings of the IEEE International Ultrasonics Symposium (Beijing, China), November 2 to 5, 2008
  • Download Full Text (PDF) | Download Citation (BibTeX)
  • In vivo validation of 2-D myocardial elastography at variable levels of ischemia
  • Wei-Ning Lee, Jean Provost, Shougang Wang, Kana Fujikura, Jie Wang, Elisa E. Konofagou
  • Proceedings of the IEEE International Ultrasonics Symposium (Beijing, China), November 2 to 5, 2008
  • Download Full Text (PDF) | Download Citation (BibTeX)
  • Fundamental performance assessment of 2-D myocardial elastography in a phased array configuration
  • Jianwen Luo, Wei-Ning Lee, Elisa E. Konofagou
  • Proceedings of the IEEE International Ultrasonics Symposium (Beijing, China), November 2 to 5, 2008
  • Download Full Text (PDF) | Download Citation (BibTeX)
  • A composite high frame-rate system for clinical cardiovascular imaging
  • Shougang Wang, Wei-Ning Lee, Jean Provost, Jianwen Luo, Elisa E. Konofagou
  • IEEE International Ultrasonics Symposium (Beijing, China), November 2 to 5, 2008
  • Download Citation (BibTeX)
  • Electromechanical wave propagation in the normal and ischemic canine myocardium in vivo
  • Jean Provost, Wei-Ning Lee, Kana Fujikura, Elisa E. Konofagou
  • 7th International Tissue Elasticity Conference (Austin, TX, USA), October 27 to 30, 2008
  • Download Citation (BibTeX)
  • The effect of frame rate on image quality of myocardial elastography in vivo
  • Jianwen Luo, Wei-Ning Lee, Shougang Wang, Elisa E. Konofagou
  • 6th International Tissue Elasticity Conference (Santa Fe, NM, USA), November 2 to 5, 2007
  • Download Citation (BibTeX)
  • Importance of principal strain estimation in clinical myocardial elastography with validation against MRI tagging
  • Wei-Ning Lee, Zhen Qian, Dimitris N. Metaxas, Elisa E. Konofagou
  • 6th International Tissue Elasticity Conference (Santa Fe, NM, USA), November 2 to 5, 2007
  • Download Citation (BibTeX)
  • Experimental assessment of angle-independent myocardial elastography performance using a left-ventricular phantom under physiologic motion
  • Viktor Gamarnik, Jianwen Luo, Wei-Ning Lee, Elisa E. Konofagou
  • Proceedings of the IEEE International Ultrasonics Symposium (New York, NY, USA), October 28 to 31, 2007
  • Download Full Text (PDF) | Download Citation (BibTeX)
  • Clinical validation of angle-independent myocardial elastography using MRI tagging
  • Wei-Ning Lee, Zhen Qian, Dimitris N. Metaxas, Elisa E. Konofagou
  • Proceedings of the IEEE International Ultrasonics Symposium (New York, NY, USA), October 28 to 31, 2007
  • Download Full Text (PDF) | Download Citation (BibTeX)
  • An in-vivo study of frame rate optimization for myocardial elastography
  • Jianwen Luo, Wei-Ning Lee, Shougang Wang, Elisa E. Konofagou
  • Proceedings of the IEEE International Ultrasonics Symposium (New York, NY, USA), October 28 to 31, 2007
  • Download Full Text (PDF) | Download Citation (BibTeX)
  • A composite imaging technique for high framerate and full-view cardiovascular ultrasound and elasticity imaging
  • Shougang Wang, Wei-Ning Lee, Jianwen Luo, Elisa E. Konofagou
  • Proceedings of the IEEE International Ultrasonics Symposium (New York, NY, USA), October 28 to 31, 2007
  • Download Full Text (PDF) | Download Citation (BibTeX)
  • Validation of 2D ultrasound-based strain estimates with MR tagging
  • Wei-Ning Lee, Zhen Qian, Christina L. Tosti, Truman R. Brown, Dimitris N. Metaxas, Elisa E. Konofagou
  • Proceedings of the Annual Meeting of the International Society for Magnetic Resonance in Medicine (Berlin, Germany), May 19 to 25, 2007
  • Download Full Text (PDF) | Download Citation (BibTeX)
  • Validation of ultrasound myocardial elastography using MR tagging in normal and abnormal human hearts in vivo
  • Wei-Ning Lee, Zhen Qian, Christina L. Tosti, Truman R. Brown, Dimitris N. Metaxas, Elisa E. Konofagou
  • Proceedings of the IEEE International Symposium on Biomedical Imaging (Washington, DC, USA), April 12 to 15, 2007
  • Download Full Text (PDF) | Download Citation (BibTeX)
  • Angle-independent and multi-dimensional myocardial elastography: from theory to clinical validation
  • Wei-Ning Lee, Elisa E. Konofagou
  • International Congress on Ultrasonics (Vienna, Austria), April 9 to 12, 2007
  • Download Citation (BibTeX)
  • Angle-independent myocardial elastography: theoretical analysis and clinical validation
  • Elisa E. Konofagou, Wei-Ning Lee, Simon D. Fung-Kee-Fung
  • Proceedings of the IEEE SPIE Medical Imaging Conference (San Diego, CA, USA), February 17 to 22, 2007
  • Download Full Text (PDF) | Download Citation (BibTeX)
  • Analysis of 3D motion effects in 2D myocardial elastography
  • Wei-Ning Lee, Elisa E. Konofagou
  • Proceedings of the IEEE International Ultrasonics Symposium (Vancouver, BC, Canada), October 2 to 5, 2006
  • Download Full Text (PDF) | Download Citation (BibTeX)
  • Principal strain imaging for the detection of infarcts
  • Elisa E. Konofagou, Simon D. Fung-Kee-Fung, Wei-Ning Lee
  • Society of Industrial and Applied Mathematics Annual Meeting (Boston, MA, USA), July 7 to 10, 2006
  • Invited Contribution
  • Download Citation (BibTeX)
  • A 3D simulation model for performance assessment of 2D myocardial elastography
  • Wei-Ning Lee, Christopher M. Ingrassia, Elisa E. Konofagou
  • 4th International Tissue Elasticity Conference (Austin, TX, USA), October 17 to 20, 2005
  • Download Citation (BibTeX)
  • Angle-independent strain mapping in myocardial elastography: 2-D strain tensor characterization and principal component imaging
  • Simon D. Fung-Kee-Fung, Wei-Ning Lee, Christopher M. Ingrassia, Kevin D. Costa, Elisa E. Konofagou
  • Proceedings of the IEEE International Ultrasonics Symposium (Rotterdam, The Netherlands), September 17 to 20, 2005
  • Download Full Text (PDF) | Download Citation (BibTeX)
  • A theoretical performance assessment tool for myocardial elastography
  • Elisa E. Konofagou, Wei-Ning Lee, Christopher M. Ingrassia
  • Proceedings of the 27th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (Shanghai, China), September 1 to 4, 2005
  • Invited Contribution
  • Download Full Text (PDF) | Download Citation (BibTeX)
  • Full strain tensor representation in myocardial elastography
  • Elisa E. Konofagou, Wei-Ning Lee
  • Society of Industrial and Applied Mathematics Annual Meeting (New Orleans, LA, USA), July 11 to 15, 2005
  • Invited Contribution
  • Download Citation (BibTeX)

Thesis

  • Myocardial elastography: a strain imaging technique for the reliable detection and localization of myocardial ischemia in vivo
  • Wei-Ning Lee
  • Ph.D. Thesis, Columbia University (New York, NY, USA), 2010
  • Download Full Text (PDF) | Download Citation (BibTeX)

Book Chapter

  • Cardiovascular elasticity imaging
  • Elisa E. Konofagou, Wei-Ning Lee, Jianwen Luo
  • Chapter 6 of Biomedical applications of vibration and acoustics in imaging and characterizations (ASME Press, New York, NY, USA), Pages 93-117, 2008
  • Download Citation (BibTeX)

From the website of the Ultrasound Elasticity Imaging Laboratory at Columbia University.
Source: orion.bme.columbia.edu/ueil/person.php
Date: May 18, 2013 at 4:29 PM
Copyright © 2013 Columbia University.

Results

images/results/bbb/2012-samiotaki-bbb-reversibility-fig2.jpg

Reversible blood-brain barrier opening using focused ultrasound. More… »

images/results/ewi/2012-konofagou-ewi-3d-in-vivo-fig8.jpg

EWI isochrones of a normal sinus rhythm obtained noninvasively in a normal human subject. More… »

images/results/pwi/2010-vappou-pwi-quantitative-fig4a.gif

An example of pulse wave propagation in a human aorta. More… »

images/results/mye/2011-luo-wall-motion-fig4b.jpg

M-mode of wall velocity and blood velocity in infarcted hearts. More… »

images/results/bbb/2010-deffieux-bbb-transcranial-fig8.jpg

Maximum pressure field at 500 kHz when targeting the putamen through the human skull. More… »

images/results/hmi/2010-maleke-hmi-real-time-fig5b.jpg

M-mode of a tumor during ablation with HMIFU. More… »

images/results/mye/2009-luo-mye-performance-fig2ab.jpg

Radial and circumferential strains from finite-element solution and from elastographic estimation. More… »

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Recent Papers

  • Pulse Wave Imaging (PWI) in normal, hypertensive and aneurysmal human aortas in vivo: a feasibility study (Physics in Medicine and Biology)
  • Mapping the longitudinal wall stiffness heterogeneities within intact canine aortas using Pulse Wave Imaging (PWI) ex vivo (Journal of Biomechanics)
  • An Experimental Study on the Stiffness of Size-Isolated Microbubbles Using Atomic Force Microscopy (IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control)

View all papers… »

Upcoming Presentations

  • 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (Osaka, Japan; July 3 to 7, 2013)
  • IEEE International Ultrasonics Symposium (Prague, Czech Republic; July 21 to 25, 2013)

View all presentations… »


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Columbia University Medical Campus
630 West 168th Street
Physicians & Surgeons 19-418
New York, NY, USA 10032

Phone: +1 212 342 0863
Fax: +1 212 342 1648

The mission of the UEIL is to develop new ultrasound-based
techniques for both imaging and therapeutic applications.

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