Yao-Sheng Tung, Ph.D. (Former Ph.D. Student)

Academic Qualifications

• Ph.D., Biomedical Engineering, Columbia University (New York, NY, USA), 2012
• M.S., Biomedical Engineering, National Taiwan University (Taipei, Taiwan), 2005
• B.S., Business Administration, National Taiwan University (Taipei, Taiwan), 2001

Biography

Yao-Sheng Tung was born in Taipei, Taiwan. He received his B.S. and M.S. degrees from National Taiwan University, in Taipei, Taiwan. He was a research assistant in National Taiwan University Hospital in 2006. In September 2007, he enrolled in Columbia University's Ph.D. program. Yao-Sheng's research interests are in ultrasound therapy with microbubbles, and cavitation effects. He obtained his Ph.D. in 2012 and continued to work in the UEIL as a postdoctoral research scientist.

Awards and Prizes

• Thesis distinction (Columbia University), 2012
• Yuen-Huo Hung and Chaochin Huang award in biomedical engineering (given anually to the top graduating Ph.D. student in the Department of Biomedical Engineering of Columbia University), 2012
• Best poster award (The New York Academy of Sciences), 2011
• Nadine Barrie Smith student award (first prize of the student competition at the International Symposium on Therapeutic Ultrasound), 2011
• Student travel support award (IEEE International Ultrasonics Symposium), 2010

Publications

To obtain a bibliography of all of Dr. Tung's publications, click here to download the complete list (in BibTeX format).

Journal Articles

	Ultrasound-induced blood-brain barrier opening Elisa E. Konofagou, Yao-Sheng Tung, James J. Choi, Thomas Deffieux, Jameel A. Feshitan, Mark A. Borden, Babak Baseri, Fotis Vlachos Current Pharmaceutical Biotechnology, September 2012 Invited Contribution Download Citation (BibTeX)
	Activation of signaling pathways following localized delivery of systemically administered neurotrophic factors across the blood-brain barrier using focused ultrasound and microbubbles Babak Baseri, James J. Choi, Thomas Deffieux, Gesthimani Samiotaki, Yao-Sheng Tung, Oluyemi O. Olumolade, Scott A. Small, Barclay Morrison III, Elisa E. Konofagou Physics in Medicine and Biology, Volume 57, Number N, Pages 65-81, March 2012 Digital Object Identifier: 10.1088/0031-9155/57/7/N65 Download Full Text (PDF) | Download Citation (BibTeX)
	A quantitative pressure and microbubble-size dependence study of focused ultrasound-induced blood-brain barrier opening reversibility in vivo using MRI Gesthimani Samiotaki, Fotis Vlachos, Yao-Sheng Tung, Elisa E. Konofagou Magnetic Resonance in Medicine, Volume 67, Number 3, Pages 769-777, March 2012 Digital Object Identifier: 10.1002/mrm.23063 Download Full Text (PDF) | Download Citation (BibTeX)
	The mechanism of interaction between focused ultrasound and microbubbles in blood-brain barrier opening in mice Yao-Sheng Tung, Fotis Vlachos, Jameel A. Feshitan, Mark A. Borden, Elisa E. Konofagou Journal of the Acoustical Society of America, Volume 130, Number 5, Pages 3059-3067, November 2011 Digital Object Identifier: 10.1121/1.3646905 Download Full Text (PDF) | Download Citation (BibTeX)
	Non-invasive, transient and selective blood-brain barrier opening in non-human primates in vivo Fabrice Marquet, Yao-Sheng Tung, Tobias Teichert, Vincent P. Ferrera, Elisa E. Konofagou PLoS One, Volume 6, Number 7, e. 22598, July 2011 Digital Object Identifier: 10.1371/journal.pone.0022598 Download Full Text (PDF) | Download Citation (BibTeX)
	Permeability dependence study of the focused ultrasound-induced blood-brain barrier opening at distinct pressures and microbubble diameters using DCE-MRI Fotis Vlachos, Yao-Sheng Tung, Elisa E. Konofagou Magnetic Resonance in Medicine, Volume 66, Pages 821-830, April 2011 Digital Object Identifier: 10.1002/mrm.22848 Download Full Text (PDF) | Download Citation (BibTeX)
	Feasibility of cavitation-guided blood-brain barrier opening using FUS and microbubbles in non-human primates Yao-Sheng Tung, Fabrice Marquet, Tobias Teichert, Vincent P. Ferrera, Elisa E. Konofagou Applied Physics Letters, Volume 98, Number 16, e. 163704, April 2011 Digital Object Identifier: 10.1063/1.3580763 Download Full Text (PDF) | Download Citation (BibTeX)
	In vivo transcranial cavitation threshold detection during ultrasound-induced blood-brain barrier opening Yao-Sheng Tung, Fotis Vlachos, James J. Choi, Thomas Deffieux, Kirsten Selert, Elisa E. Konofagou Physics in Medicine and Biology, Volume 55, Number 20, Pages 6141-6155, October 2010 Digital Object Identifier: 10.1088/0031-9155/55/20/007 Download Full Text (PDF) | Download Citation (BibTeX)
	Permeability assessment of the focused ultrasound-induced blood-brain barrier opening using dynamic contrast-enhanced MRI Fotis Vlachos, Yao-Sheng Tung, Elisa E. Konofagou Physics in Medicine and Biology, Volume 55, Number 18, Pages 5451-5466, September 2010 Digital Object Identifier: 10.1088/0031-9155/55/18/012 Download Full Text (PDF) | Download Citation (BibTeX)
	Multi-modality safety assessment of blood-brain barrier opening using focused ultrasound and Definity microbubbles: a short-term study Babak Baseri, James J. Choi, Yao-Sheng Tung, Elisa E. Konofagou Ultrasound in Medicine and Biology, Volume 36, Number 9, Pages 1445-1459, September 2010 Digital Object Identifier: 10.1016/j.ultrasmedbio.2010.06.005 Download Full Text (PDF) | Download Citation (BibTeX)
	Identifying the inertial cavitation threshold and skull effects in a vessel phantom using focused ultrasound and microbubbles Yao-Sheng Tung, James J. Choi, Babak Baseri, Elisa E. Konofagou Ultrasound in Medicine and Biology, Volume 36, Number 5, Pages 840-852, May 2010 Digital Object Identifier: 10.1016/j.ultrasmedbio.2010.02.009 Download Full Text (PDF) | Download Citation (BibTeX)
	Molecules of various pharmacologically-relevant sizes can cross the ultrasound-induced blood-brain barrier opening in vivo James J. Choi, Shougang Wang, Yao-Sheng Tung, Barclay Morrison III, Elisa E. Konofagou Ultrasound in Medicine and Biology, Volume 36, Number 1, Pages 58-67, January 2010 Digital Object Identifier: 10.1016/j.ultrasmedbio.2009.08.006 Download Full Text (PDF) | Download Citation (BibTeX)
	Microbubble-size dependence of focused ultrasound-induced blood-brain barrier opening in mice in vivo James J. Choi, Jameel A. Feshitan, Babak Baseri, Shougang Wang, Yao-Sheng Tung, Mark A. Borden, Elisa E. Konofagou IEEE Transactions on Biomedical Engineering, Volume 57, Number 1, Pages 145-154, January 2010 Digital Object Identifier: 10.1109/TBME.2009.2034533 Download Full Text (PDF) | Download Citation (BibTeX)
	Feasibility study of a clinical blood-brain barrier opening ultrasound system Fabrice Marquet, Yao-Sheng Tung, Elisa E. Konofagou NanoLife, Volume 1, Number 3-4, Pages 309-322, 2010 Digital Object Identifier: 10.1142/S1793984410000286 Download Full Text (PDF) | Download Citation (BibTeX)

Conference Papers and Presentations

	Monitoring of FUS-induced BBB opening in non-human primates using transcranial cavitation detection in vivo and the human skull effect Shih-Ying Wu, Fabrice Marquet, Yao-Sheng Tung, Tobias Teichert, Matthew E. Downs, Cherry C. Chen, Vincent P. Ferrera, Elisa E. Konofagou IEEE International Ultrasonics Symposium (Prague, Czech Republic), July 21 to 25, 2013 Download Citation (BibTeX)
	The cavitation-dependent zonula-occludens-1 integrity after ultrasound-induced blood-brain barrier opening Yao-Sheng Tung, Cherry C. Chen, Oluyemi O. Olumolade, Shih-Ying Wu, Shutao Wang, Elisa E. Konofagou Cold Spring Harbor Laboratory Meeting: The Blood-Brain Barrier (Cold Spring Harbor, NY, USA), December 5 to 8, 2012 Download Citation (BibTeX)
	Quantification of stable cavitation dose during FUS-induced blood-brain barrier opening in mice and in non-human primates Yao-Sheng Tung, Shih-Ying Wu, Fabrice Marquet, Elisa E. Konofagou IEEE International Ultrasonics Symposium (Dresden, Germany), October 7 to 10, 2012 Download Citation (BibTeX)
	Non-human primate skull effects on the FUS-induced blood-brain barrier opening Shih-Ying Wu, Yao-Sheng Tung, Fabrice Marquet, Cherry C. Chen, Elisa E. Konofagou IEEE International Ultrasonics Symposium (Dresden, Germany), October 7 to 10, 2012 Download Citation (BibTeX)
	Physical mechanism of non-inertial cavitation induced blood-brain barrier opening using focused ultrasound and microbubbles Yao-Sheng Tung, Oluyemi O. Olumolade, Shutao Wang, Shih-Ying Wu, Elisa E. Konofagou 12th International Symposium on Therapeutic Ultrasound (Heidelberg, Germany), June 10 to 13, 2012 Download Citation (BibTeX)
	Non-human primate skull effects on the in vivo study of the mechanism of the FUS-induced blood-brain barrier opening Shih-Ying Wu, Yao-Sheng Tung, Fabrice Marquet, Elisa E. Konofagou 12th International Symposium on Therapeutic Ultrasound (Heidelberg, Germany), June 10 to 13, 2012 Download Citation (BibTeX)
	Microbubble-enhanced focused ultrasound blood-brain barrier opening in non-human primates: targeting accuracy and closing timeline Fabrice Marquet, Yao-Sheng Tung, Tobias Teichert, Vincent P. Ferrera, Elisa E. Konofagou 12th International Symposium on Therapeutic Ultrasound (Heidelberg, Germany), June 10 to 13, 2012 Download Citation (BibTeX)
	Permeability and reversibility timeline study of the focused-ultrasound induced blood-brain barrier opening at distinct pressures and microbubble sizes in vivo Gesthimani Samiotaki, Fotis Vlachos, Yao-Sheng Tung, Elisa E. Konofagou IEEE International Ultrasonics Symposium (Orlando, FL, USA), October 18 to 21, 2011 Download Citation (BibTeX)
	Mechanism monitoring of noninvasive cavitation-guided blood-brain barrier opening using focused ultrasound and microbubbles in non-human primates Yao-Sheng Tung, Fabrice Marquet, Tobias Teichert, Vincent P. Ferrera, Elisa E. Konofagou IEEE International Ultrasonics Symposium (Orlando, FL, USA), October 18 to 21, 2011 Download Citation (BibTeX)
	Initial in vivo feasibility of a simple pre-clinical focused ultrasound system applied to blood-brain barrier opening Fabrice Marquet, Yao-Sheng Tung, Tobias Teichert, Vincent P. Ferrera, Elisa E. Konofagou IEEE International Ultrasonics Symposium (Orlando, FL, USA), October 18 to 21, 2011 Download Citation (BibTeX)
	Bubble dependence of the mechanism for FUS-induced blood-brain barrier opening in mice in vivo Yao-Sheng Tung, Fotis Vlachos, Kirsten Selert, Elisa E. Konofagou 161st Meeting of the Acoustical Society of America (Seattle, WA, USA), May 23 to 27, 2011 Shortlisted for the Best Student Paper Competition Download Citation (BibTeX)
	Pressure and microbubble-size dependence of the FUS-induced blood brain barrier opening reversibility in vivo Gesthimani Samiotaki, Fotis Vlachos, Yao-Sheng Tung, Elisa E. Konofagou Annual Meeting of the International Society for Magnetic Resonance in Medicine (Montreal, QC, Canada), May 7 to 13, 2011 Download Citation (BibTeX)
	In vivo identification of the mechanism behind ultrasound-induced blood-brain barrier opening Yao-Sheng Tung, Fotis Vlachos, Kirsten Selert, Elisa E. Konofagou American Institute of Ultrasound in Medicine Annual Convention (New York, NY, USA), April 14 to 17, 2011 Download Citation (BibTeX)
	Feasibility of a simple transcranial focused ultrasound system for blood-brain barrier opening Fabrice Marquet, Yao-Sheng Tung, Fotis Vlachos, Elisa E. Konofagou American Institute of Ultrasound in Medicine Annual Convention (New York, NY, USA), April 14 to 17, 2011 Download Citation (BibTeX)
	The bubble-dependent mechanism of FUS-induced blood-brain barrier opening in mice in vivo Yao-Sheng Tung, Fotis Vlachos, Jameel A. Feshitan, Mark A. Borden, Elisa E. Konofagou 11th International Symposium on Therapeutic Ultrasound (New York, NY, USA), April 11 to 13, 2011 Winner of the Best Student Paper Competition Download Citation (BibTeX)
	Pressure and microbubble size dependence study of focused ultrasound-induced blood-brain barrier opening reversibility in vivo Gesthimani Samiotaki, Fotis Vlachos, Yao-Sheng Tung, Elisa E. Konofagou 11th International Symposium on Therapeutic Ultrasound (New York, NY, USA), April 11 to 13, 2011 Download Citation (BibTeX)
	Feasibility of a single-element transcranial focused ultrasound system for blood-brain barrier opening Fabrice Marquet, Yao-Sheng Tung, Fotis Vlachos, Elisa E. Konofagou 11th International Symposium on Therapeutic Ultrasound (New York, NY, USA), April 11 to 13, 2011 Download Citation (BibTeX)
	In-vivo quantitative permeability assessment of the focused-ultrasound-induced blood-brain barrier opening using dynamic contrast-enhanced MRI Fotis Vlachos, Yao-Sheng Tung, Elisa E. Konofagou IEEE International Ultrasonics Symposium (San Diego, CA, USA), October 11 to 14, 2010 Download Citation (BibTeX)
	In vivo transcranial cavitation detection during ultrasound-induced blood-brain barrier opening Yao-Sheng Tung, Fotis Vlachos, Thomas Deffieux, James J. Choi, Kirsten Selert, Elisa E. Konofagou IEEE International Ultrasonics Symposium (San Diego, CA, USA), October 11 to 14, 2010 Shortlisted for the Best Student Paper Competition Download Citation (BibTeX)
	MR-based pharmacokinetics of the focused-ultrasound-induced blood-brain barrier Opening Fotis Vlachos, Yao-Sheng Tung, Elisa E. Konofagou Biomedical Engineering Society Annual Meeting (Austin, TX, USA), October 6 to 9, 2010 Download Citation (BibTeX)
	Noninvasive in vivo cavitation threshold detection during blood-brain barrier opening using focused ultrasound and Definity Yao-Sheng Tung, Fotis Vlachos, Thomas Deffieux, James J. Choi, Elisa E. Konofagou 159th Meeting of the Acoustical Society of America (Baltimore, MD, USA), April 19 to 23, 2010 Download Citation (BibTeX)
	Quantitative assessment of in vivo focused ultrasound induced blood-brain barrier opening using Magnetic Resonance Imaging Gesthimani Samiotaki, Fotis Vlachos, Yao-Sheng Tung, Elisa E. Konofagou Northeast Bioengineering Conference (New York, NY, USA), March 26 to 28, 2010 Download Citation (BibTeX)
	Identifying the skull effects to the inertial cavitation threshold of microbubbles in a vessel phantom Yao-Sheng Tung, James J. Choi, Elisa E. Konofagou Northeast Bioengineering Conference (New York, NY, USA), March 26 to 28, 2010 Download Citation (BibTeX)
	Delivery of pharmacologically-relevant sized molecules through the ultrasound-induced blood-brain barrier opening in vivo James J. Choi, Shougang Wang, Yao-Sheng Tung, Babak Baseri, Barclay Morrison III, Elisa E. Konofagou Neuroscience (Chicago, IL, USA), October 17 to 21, 2009 Download Citation (BibTeX)
	Mechanism and safety of FUS-induced BBB opening Elisa E. Konofagou, James J. Choi, Babak Baseri, Yao-Sheng Tung 9th International Symposium on Therapeutic Ultrasound (Aix-en-Provence, France), September 23 to 26, 2009 Download Citation (BibTeX)
	Identifying the inertial cavitation threshold of monodispersed microbubbles and skull effects in a vessel phantom using focused ultrasound Yao-Sheng Tung, James J. Choi, Elisa E. Konofagou 9th International Symposium on Therapeutic Ultrasound (Aix-en-Provence, France), September 23 to 26, 2009 Download Citation (BibTeX)
	Brain region and microbubble-size dependence of the focused ultrasound-induced blood-brain barrier opening in mice in vivo James J. Choi, Jameel A. Feshitan, Babak Baseri, Shougang Wang, Yao-Sheng Tung, Mark A. Borden, Elisa E. Konofagou IEEE International Ultrasonics Symposium (Rome, Italy), September 18 to 21, 2009 Download Citation (BibTeX)
	Qualitative and quantitative analysis of the molecular delivery through the ultrasound-enhanced blood-brain barrier opening in the murine brain Shougang Wang, James J. Choi, Yao-Sheng Tung, Barclay Morrison III, Elisa E. Konofagou IEEE International Ultrasonics Symposium (Beijing, China), November 2 to 5, 2008 Download Citation (BibTeX)
	The dependence of the ultrasound-induced blood-brain barrier opening characteristics on microbubble size in vivo James J. Choi, Jameel A. Feshitan, Shougang Wang, Yao-Sheng Tung, Babak Baseri, Mark A. Borden, Elisa E. Konofagou 8th International Symposium on Therapeutic Ultrasound (Minneapolis, MN, USA), September 10 to 13, 2008 Download Citation (BibTeX)
	Qualitative and quantitative analysis of molecular delivery through the ultrasound-induced blood-brain barrier opening in mice Shougang Wang, Babak Baseri, James J. Choi, Yao-Sheng Tung, Barclay Morrison III, Elisa E. Konofagou 8th International Symposium on Therapeutic Ultrasound (Minneapolis, MN, USA), September 10 to 13, 2008 Download Citation (BibTeX)
	Trans-blood-brain barrier delivery of compounds at pharmacologically relevant molecular weights in the hippocampus of mice using focused ultrasound James J. Choi, Shougang Wang, Yao-Sheng Tung, Barclay Morrison III, Elisa E. Konofagou 155th Meeting of the Acoustical Society of America (Paris, France), June 29 to July 4, 2008 Download Citation (BibTeX)
	Identifying the inertial cavitation threshold in a vessel phantom using FUS and microbubbles Yao-Sheng Tung, James J. Choi, Shougang Wang, Jameel A. Feshitan, Mark A. Borden, Elisa E. Konofagou 155th Meeting of the Acoustical Society of America (Paris, France), June 29 to July 4, 2008 Download Citation (BibTeX)