Our research focuses on capturing functional information about living tissues using optical techniques. A major theme of our lab is in-vivo neuroimaging, in particular examination of the relationship between blood flow changes in the brain and underlying neuronal activity. This work has led us to develop a range of advanced in-vivo imaging technologies including laminar optical tomography and hyperspectral two-photon microscopy. We are exploring additional applications for these technologies including clinical and pre-clinical imaging of living skin. We are also developing techniques for non-invasive 'molecular imaging' of small animals to allow improved studies of disease and development of new treatments and drugs. The sections below provide more details about our projects and imaging technologies.