Mayya, V., Judokusumo, E., Abu-Shah, E., Neiswanger, W., Sachar, C., Depoil, D., Kam, L.C., and Dustin, M.L., "Cutting Edge: Synapse Propensity of Human Memory CD8 T Cells Confers Competitive Advantage over Naive Counterparts", J Immunol, 203 (2019). link
Tamzalit, F., Wang, M.S., Jin, W., Tello-Lafoz, M., Boyko, V., Heddleston, J.M., Black, C.T., Kam, L.C., and Huse, M., "Interfacial actin protrusions mechanically enhance killing by cytotoxic T cells", Science Immunol, 4 (2019). link
Jin, W., Tamzalit, F., Chaudhuri, P. Kant, Black, C.T., Huse, M., and Kam, L.C., "T cell activation and immune synapse organization respond to the microscale mechanics of structured surfaces", PNAS, 116: 19835-40 (2019). link
Dang, A.P., De Leo, S., Bogdanowicz, D.R., Yuan, D.J., Fernandes, S.M., Brown, J.R., Lu, H.H., and Kam, L.C., "Enhanced Activation and Expansion of T Cells Using Mechanically Soft Elastomer Fibers", Adv Biosystems, 2: 1700167 (2018). link
Mayya, V., Judokusumo, E., Abu Shah, E., Peel, C.G., Neiswanger, W., Depoil, D., Blair, D., Wiggins, C.H., Kam, L.C., and Dustin, M.L., Cell Reports, 22: 340-9 (2018). link
Lambert, L.H., Goebrecht, G.K.E., De Leo, S.E., O'Connor, R.S., Nunez-Cruz, S., Li, T.-D., Yuan, J., Milone, M.C., and Kam, L.C., "Improving T Cell Expansion with a Soft Touch", Nano Lett., 17: 821-6 (2017). link
Basu, R., Whitlock, B.M., Husson, J., Le Floc'h, A., Jin, W., Dotiwala, F., Giannone, G., Hivroz, C., Lieberman, J., Kam, L.C., and Huse, M. "Cytotoxic T cells use mechanical force to potentiate target cell killing", Cell 165: 1-11 (2016). link
Lee, J.H., Dustin, M.L., and Kam, L.C., "A microfluidic platform reveals differential response of regulatory T cells to micropatterned costimulation arrays", Integrative Biology, 7: 1442-53 (2015). link
Tabdanov, E., Gondarenko, S., Kumari, S., Liapis, A., Dustin, M.L., Sheetz, M.P., Kam, L.C., and Iskratch, T., "Micropatterning of TCR and LFA-1 ligands reveals complementary effects on cytoskeleton mechanics in T cells", Integrative Biology, 7: 1272-84 (2015). link
Kumari, S., Depoli, D., Martinelli, R., Judokusumo, E., Carmona, G., Gertler, F., Kam, L.C., Carman, C.V. Burkhardt, J.K., Irvine, D.J., and Dustin, M. L., "Actin foci facilitate activation of the phospholipase C-gamma in primary T lymphocytes via the WASP pathway", eLife, 4:e04953 (2015). link
Choudhuri, K., Llodra, J., Roth, E.W., Tsai, J., Gordo, S., Wucherphfenning, K.W., Kam, L.C., Stokes, D.L., and Dustin, M.L., "Polarized release of T-cell-receptor-enriched microvesicles at the immunological synapse", Nature, 507: 118-23 (2014), link
Bashour, K.T., Gondarenko, A., Chen, H., She, K., Liu, X., Huse, M., Hone, J.C., and Kam, L.C., "CD28 and CD3 have complementary roles in T-cell traction forces", PNAS, 111: 2241-6 (2014), link
Bashour, K.T., Tsai, J., Shen, K., Lee, J-H., Sun, E., Milone, M.C., Dustin, M.L., and Kam, L.C., "Crosstalk between CD3 and CD28 is spatially modulated by protein lateral mobility", Mol Cell Biol, 34: 955-64 (2014), link
Wang, Y., Xu, Z., Kam, L.C., and Shi. P., "Site-specific differentiation of neural stem cell regulated by micropatterned multicomponent Interfaces", Adv Healthcare Mat, 3: 214-20 (2014), link
Kam, L.C., Shen, K., and Dustin, M.L., "Micro- and nanoscale engineering of cell signaling", Ann Rev Biomed Eng, 15:305-26 (2013). link
O'Connor, R.S., Hao, X., Shen, K., Bashour, K., Akimova, T., Hancock, W.W., Kam, L.C., and Milone, M.C., "Substrate rigidity regulates human T cell activation and proliferation", J Immunol, 189: 1330-9 (2012). link
Judokusumo, E., Tabdanov, E., Kumari, S., Dustin, M.L., and Kam, L.C., "Mechanosensing in T lymphocyte activation", Biophysical Journal – Letters, 102:L5-7 (2012). link
Nedelec, S., Peljto, M., Shi. P., Amoroso, M.W., Kam, L.C., and Wichterle, H., "Concentration dependent requirement for local protein synthesis in motor neuron subtype specific response to axon guidance cues", J Neurosci, 32: 1496-506 (2012).
Lei, N., Ramakrishnan, S., Shi, P., Orcuttc, J.S., Yuste, R., Kam, L.C., and Shepard, K.L. "High-resolution extracellular stimulation of dispersed hippocampal culture with high-density CMOS multielectrode array based on non-Faradaic electrodes." J Neural Eng, 8:044003 (2011). link
Shi, P., Nedelec, S., Wichterle, H., and Kam, L.C., "Combined Microfluidics/protein Patterning Platform for Pharmacological Interrogation of Axon Pathfinding," Lab Chip, 10:1005-10 (2010). link
Shen, K., Tsai, J., Shi, P., Kam, L.C., "Self-aligned Supported Lipid Bilayers for Patterning the Cell-Substrate Interface," JACS, 131:13204-5 (2009). link
Tsai, J., and Kam, L.C., "Rigidity-dependent Crosstalk Between Integrin and Cadherin Signaling," Biophys J - Biophys Lett. 96: L39-41 (2009). link
Shen, K., Qi, J., and Kam, L.C., "Microcontact Printing of Proteins for Cell Biology,"JoVE 22. (2008). link
Shen, K., Thomas, V.K., Dustin, M.L., and Kam, L.C., "Micropatterning of costimulatory ligands enhances CD4+ T cell function," PNAS 105: 7791-6. (2008). link
Tsai, J., Sun, E., Gao, Y., Hone, J.C., Kam, L.C., "Non-brownian diffusion of membrane molecules in nanopatterned supported lipid bilayers.," Nano Letters 8: 425-30. (2008). link
Shi, P., Shen, K, and Kam, L.C., "Local presentation of L1 and N-cadherin in multicomponent, microscale patterns differentially direct neuron function in vitro.," Developmental Neurobiology 67: 1765-76.link
Perez, T.D., Nelson, W.J., Boxer, S.G., and Kam, L., “E-cadherin Tethered to Supported Lipid Bilayers as a Model for Cell Adhesion,” Langmuir, 21: 11963-8 (2005). link
Kam, L., and Boxer, S.G., “Spatially Selective Manipulation of Supported Lipid Bilayers by Laminar Flow: Steps Towards Biomembrane Microfluidics,” Langmuir, 19: 1624-1631 (2003). link
Ajo-Franklin, C.M., Kam, L., and Boxer, S.G., “High Refractive Index Substrates for Fluorescence Microscopy of Biological Interfaces with High z-Resolution,” Proceedings of the National Academy of Sciences, USA, 98: 13643-13648 (2001). link
Kam, L., and Boxer, S.G., “Cell Adhesion to Protein-micropatterned Supported Lipid Bilayer Membranes,” Journal of Biomedical Materials Research 55: 487-495 (2001). link
Kam, L., Shain, W., Turner, J.N., and Bizios, R., “Axonal Outgrowth of Hippocampal Neurons on Micro-Scale Networks of Polylysine-Conjugated Laminin,” Biomaterials 22: (2001) 1049-1054 (2001). link
Kam, L., and Boxer, S.G., “Formation of Supported Lipid Bilayer Composition Arrays by Controlled Mixing and Surface Capture,” Journal of the American Chemical Society 122: 12901-12902 (2000). link
Kung, L.A., Kam, L., Hovis, J.S., and Boxer, S.G., “Patterning Hybrid Surfaces of Proteins and Supported Lipid Bilayers,” Langmuir 16:6773-6776 (2000). link
James, C.D., Davis, R.C., Meyer, M., Perez, A., Turner, S., Withers, G., Kam, L. Banker, G., Craighead, H.G., Isaacson, M., Turner, J.N., Shain, W., “Aligned Microcontact Printing of Micrometer Scale Polylysine Structures for Controlled Growth of Cultured Neuronson Planar Microelectrode Arrays,” IEEE Transactions in Biomedical Engineering 47:17-21 (2000). link
St. John, P., Kam, L., Turner, S.W., Craighead, H.G., Issacson, M., Turner, J.N., Shain, W., "Preferential Glial Cell Attachment to Microcontact-printed Surfaces," Journal of Neuroscience Methods 75: 171-177 (1997). link