> RESEARCH

Orthopaedic Interface Tissue Engineering

Soft tissue-to-bone interface are ubiquious in the body, and they are critical for joint motion and stabilization.  Following the approach outlined below for interface tissue engineering, current reearch projects focus on the junction between soft tissue (e.g. tendon, ligament, cartilage) and bone due to its functional significance in musculoskeletal motion. 

Interface Tissue Engineering Schematic

Project 1:  Ligament-to-Bone Interface Tissue Engineering: Anterior Cruciate Ligament (ACL) Grafts

Collaborators

Drs. S.P. Doty, S.A. Rodeo, A. Boskey and N. Camacho, Hospital for Special Surgery

Drs. E.E. Konofagou, X.E. Guo and C.T. Hung, Biomedical Engineering, Columbia University

Dr. F.H. Chen, National Institute of Health (NIH)

Project 2:  Tendon-to-Bone Interface Tissue Engineering: Rotator Cuff Tendon Repair

Collaborator    

Dr. W.N. Levine, Orthopaedic Surgery, Columbia University

Project 3:  Cartilage-to-Bone Interface Tissue Engineering:  Osteochondral Graft-Based Cartilage Repair

Collaborators       

Drs. C.T. Hung, G.A. Ateshian, and V.C. Mow, Columbia University

Dr. F.H. Chen, National Institute of Health (NIAMS)